Using nickel to fold discrete synthetic macromolecules into single-chain nanoparticles
نویسندگان
چکیده
Sequence-defined macromolecules were prepared with a thiolactone-based platform whereby ligand functionalities introduced along the backbone enabling nickel induced formation of single-chain nanoparticles.
منابع مشابه
Single-chain technology using discrete synthetic macromolecules.
Fundamental polymer science is undergoing a profound transformation. As a result of recent progress in macromolecular chemistry and physics, synthetic polymer chains are becoming much more than just the modest building blocks of traditional 'plastics'. Promising options for controlling the primary and secondary structures of synthetic polymers have been proposed and, therefore, similarly to bio...
متن کاملPolymer dynamics from synthetic to biological macromolecules
In soft materials entropic and enthalpic contributions are of similar magnitude and balance each other. Therefore, the macroscopic mechanical and rheological properties and the phase changes are determined to a high degree by thermal motion of the atoms and molecules. Most of the relevant dynamics takes place on mesoscopic length and time scales in between the picosecond atomic scale and the ma...
متن کاملAdvances in Single-Chain Nanoparticles for Catalysis
Enzymes are the most efficient catalysts known working in an aqueous environment near 12 room temperature. The folding of individual polymer chains to functional single-chain nanoparticles 13 (SCNPs) offers many opportunities for the development of artificial enzyme-mimic catalysts 14 showing both high catalytic activity and specificity. In this review, we highlight recent results 15 obtained i...
متن کاملAdvances in Fluorescent Single-Chain Nanoparticles.
Fluorophore molecules can be monitored by fluorescence spectroscopy and microscopy, which are highly useful and widely used techniques in cell biology, biochemistry, and medicine (e.g., biomarker analysis, immunoassays, cancer diagnosis). Several fluorescent micro- and nanoparticle systems based on block copolymer micelles and cross-linked polymer networks, quantum dots, π-conjugated polymers, ...
متن کاملMolecular Recognition‐Mediated Transformation of Single‐Chain Polymer Nanoparticles into Crosslinked Polymer Films
We describe single-chain polymer nanoparticles (SCNPs) possessing intramolecular dynamic covalent crosslinks that can transform into polymer films through a molecular recognition-mediated crosslinking process. The SCNPs utilise molecular recognition with surface-immobilised proteins to concentrate upon a substrate, bringing the SCNPs into close spatial proximity with one another and allowing th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Polymer Chemistry
سال: 2021
ISSN: ['1759-9962', '1759-9954']
DOI: https://doi.org/10.1039/d1py00229e